Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870194 | 0.89 | TRPV1 (0.49) | LCKRXFP1NLRP3NPC1RAB9A | |
| SCHEMBL6384294 | 0.87 | LCK (0.43) | LCKRXFP1NLRP3NPC1RAB9A | |
| SCHEMBL9687613 | 0.87 | L3MBTL1 (0.42) | LMNAPOLBTSHR | |
| SCHEMBL9694548 | 0.86 | HPGD (0.47) | NLRP3NPC1RAB9ALMNAHSD17B10 | |
| SCHEMBL25287119 | 0.84 | NPC1 (0.43) | LCKRXFP1NPC1RAB9ABRD9 | |
| SCHEMBL9686499 | 0.82 | ALDH1A1 (0.57) | NLRP3NPC1RAB9ALMNAHSD17B10 | |
| SCHEMBL27896996 | 0.82 | LMNA (0.40) | LCKRXFP1RAB9ABRD9METAP1 | |
| SCHEMBL1534089 | 0.81 | NPC1 (0.58) | RXFP1NPC1RAB9ABRD9LMNA | |
| SCHEMBL3439958 | 0.79 | ALDH1A1 (0.44) | LCKRXFP1NLRP3BRD9METAP1 | |
| SCHEMBL9686228 | 0.79 | KDM4E (0.46) | NLRP3NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4920129-A | Anti-ulcerative imidazopyridine compounds | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0308917-A2 | Imidazopyridine compound, a process for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |