Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685958 | 0.80 | RECQL (0.53) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL343076 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBMAPK1TSHR | |
| SCHEMBL9686336 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| SCHEMBL2616484 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBMAPK1TSHR | |
| SCHEMBL10396627 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KMT2APOLBNPC1MAPK1 | |
| SCHEMBL9377446 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBRAB9AMAPK1 | |
| SCHEMBL27452003 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBMAPK1TSHR | |
| SCHEMBL2464854 | 0.74 | PIM1 (0.58) | ALDH1A1KMT2APOLBMAPK1TSHR | |
| SCHEMBL15013633 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBMAPK1TSHR | |
| SCHEMBL40329 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KMT2APOLBMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |