Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616481 | 0.82 | RECQL (0.51) | ALDH1A1KMT2ATSHRSMN1; SMN2MAPT | |
| SCHEMBL10879548 | 0.80 | KMT2A (0.58) | ALDH1A1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL343076 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL27452003 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL9686296 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL10396627 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL29099479 | 0.73 | MAPK1 (0.44) | ALDH1A1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL15013633 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL40329 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPK1TSHRGAA | |
| SCHEMBL79163 | 0.73 | DTYMK (0.62) | ALDH1A1KMT2AMAPK1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101097-A9 | ARYL SULFONAMIDES | UNGASHE SOLOMON (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120101097-A9 | ARYL SULFONAMIDES | UNGASHE SOLOMON (US) | 2012-04-26 | — | — | US | disclosed |
| US-20110201610-A1 | ARYL SULFONAMIDES | UNGASHE SOLOMON | 2011-08-18 | — | — | US | disclosed |
| US-20110201610-A1 | ARYL SULFONAMIDES | UNGASHE SOLOMON | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201610-A1 | ARYL SULFONAMIDES | CCR2, CCL2, CX3CR1 | ALDH1A1 1258/4885KMT2A 2610/4885MAPK1 1353/4885 |
| US-20120101097-A9 | ARYL SULFONAMIDES | CCR2, CCL2, CX3CR1 | ALDH1A1 1258/4885KMT2A 2610/4885MAPK1 1353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.