Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27371673 | 0.90 | HPGD (0.44) | ALDH1A1SMN1; SMN2POLBKCNMA1 | |
| SCHEMBL7863170 | 0.83 | KCNMA1 (0.46) | ALDH1A1KMT2APKMMAPK1MEN1 | |
| SCHEMBL27373824 | 0.82 | RECQL (0.48) | ALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7869833 | 0.82 | NPC1 (0.46) | ALDH1A1KMT2AGAATSHRMEN1 | |
| SCHEMBL27371672 | 0.77 | ABL1 (0.42) | ALDH1A1GAATSHRSMN1; SMN2POLB | |
| SCHEMBL2616484 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AGAAPKMTSHR | |
| SCHEMBL343076 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KMT2AGAAPKMTSHR | |
| SCHEMBL27397510 | 0.76 | TDP1 (0.42) | ALDH1A1KMT2ATSHRMEN1POLB | |
| SCHEMBL79163 | 0.75 | DTYMK (0.62) | ALDH1A1KMT2AGAAPKMTSHR | |
| SCHEMBL9686296 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AGAAPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084747-C | Pyrrolobenzazepine * derivatives as neuroactive agents | ZENECA LTD (GB) | 2002-05-15 | — | — | CN | disclosed |
| CN-1224424-A | Azolobenzazepine derivs. as neurologically active agents | ZENECA LTD (GB) | 1999-07-28 | — | — | CN | disclosed |