Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204732 | 0.85 | HPGD (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2POLB | |
| SCHEMBL79163 | 0.85 | DTYMK (0.62) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL990659 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL3998362 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL1138798 | 0.84 | DTYMK (0.60) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL6154642 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL6397440 | 0.84 | DTYMK (0.60) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL339922 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL6395556 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL9193556 | 0.83 | DTYMK (0.46) | ALDH1A1TSHRMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241378-A | Synthesis method of chloroprocaine hydrochloride intermediate impurity | 南京斯泰尔医药科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| US-10189804-B2 | Method for producing dicarboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-01-29 | — | — | US | claimed |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-05-31 | — | — | US | claimed |
| EP-3287448-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-28 | — | — | EP | claimed |
| CN-101747300-B | Mutual prodrug and preparation method based on paclitaxel and nitrogen mustard | UNIV SHANGHAI | 2012-11-07 | — | — | CN | claimed |
| CN-101747300-A | Mutual prodrug and preparation method based on paclitaxel and nitrogen mustard | UNIV SHANGHAI | 2010-06-23 | — | — | CN | claimed |
| CN-119241378-A | Synthesis method of chloroprocaine hydrochloride intermediate impurity | 南京斯泰尔医药科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-05-07 | — | — | US | disclosed |
| CN-110894196-A | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | 百时美-施贵宝控股爱尔兰无限公司 | 2020-03-20 | — | — | CN | disclosed |
| US-10189804-B2 | Method for producing dicarboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20180244673-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-08-30 | — | — | US | disclosed |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-05-31 | — | — | US | disclosed |
| US-9975891-B2 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-22 | — | — | US | disclosed |
| EP-0261503-A1 | Heterocyclic amido derivatives of substituted benzoic acids and therapeutic compositions which contain them as active principle | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1988-03-30 | — | — | EP | disclosed |
| EP-0216028-A2 | Use of anthranilic-acid derivatives as anthelmintic medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-01 | — | — | EP | disclosed |
| EP-0086340-B1 | 3-(1H-TETRAZOL-5-YL)-4(3H)-QUINAZOLINONES | THE DOW CHEMICAL COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| US-4521430-A | VASODILATOR, ANTIISCHEMIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0128462-A1 | Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-19 | — | — | EP | disclosed |
| US-4419357-A | 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones | THE DOW CHEMICAL COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0086340-A1 | 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinones | THE DOW CHEMICAL COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244673-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | ALDH1A1 3371/4885TSHR 3713/4885MAPK1 2648/4885 |
| US-10189804-B2 | Method for producing dicarboxylic acid compound | PC, CPS1, PCCA | ALDH1A1 294/4885TSHR 3294/4885MAPK1 4122/4885 |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | PC, CPS1, PCCA | ALDH1A1 294/4885TSHR 3294/4885MAPK1 4122/4885 |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | ALDH1A1 3406/4885TSHR 3581/4885MAPK1 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.