Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538033 | 0.82 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 | |
| SCHEMBL11452911 | 0.82 | MAPT (0.63) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 | |
| SCHEMBL31048907 | 0.82 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 | |
| SCHEMBL8482804 | 0.77 | KDM4E (0.64) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11631012 | 0.76 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 | |
| SCHEMBL10813064 | 0.75 | GABRP (0.76) | MAPTSMN1; SMN2KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL10112873 | 0.75 | ALDH1A1 (0.50) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 | |
| SCHEMBL9686042 | 0.74 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL7328152 | 0.73 | GABRP (0.57) | MAPTSMN1; SMN2KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL30556513 | 0.73 | RXFP1 (0.53) | MAPTSMN1; SMN2KDM4ECYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |