Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851289 | 0.85 | MAPT (1.00) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL9563510 | 0.77 | MAPT (0.56) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL9563517 | 0.73 | MAPT (0.58) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL18080781 | 0.73 | MAPT (0.78) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL16303386 | 0.72 | KMT2A (0.77) | SMN1; SMN2L3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL7764411 | 0.70 | KMT2A (0.54) | SMN1; SMN2ALDH1A1LMNANPC1HTT | |
| SCHEMBL9422482 | 0.69 | L3MBTL1 (0.53) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL9686366 | 0.69 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| Acetic Acid SCHEMBL6271336 | 0.69 | L3MBTL1 (0.47) | SMN1; SMN2KDM4EL3MBTL1CYP1A2MAPT | |
| SCHEMBL11727445 | 0.69 | PKM (0.73) | SMN1; SMN2MAPTPKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093797-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ABERRANT ANGIOGENESIS | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
| EP-0552665-A1 | Pyrrolylbenzodiazepinones and medicines containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1993-07-28 | — | — | EP | disclosed |