SCHEMBL9687479

SCHEMBL9687479

[CH2]c1c(C)cccc1NC(=O)CC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.47
ALOX12 P18054 1/20 0.47
MAPT P10636 4/20 0.47
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC9 Q9UKV0 2/20 0.45
HDAC5 Q9UQL6 2/20 0.45
RAB9A P51151 4/20 0.45
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 3/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9686302 0.87 MAPK1 (0.57) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9685656 0.86 HPGD (0.48) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL9686240 0.85 CA1 (0.47) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL10436820 0.82 HDAC3 (0.64) HPGDMAPTHDAC3HDAC4HDAC1
SCHEMBL1818573 0.82 HPGD (0.68) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL30738307 0.82 HPGD (0.68) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL9686605 0.80 ALDH1A1 (0.66) HPGDMAPTRAB9AALDH1A1MAPK1
SCHEMBL13090977 0.80 ALDH1A1 (0.46) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL9686207 0.80 ALDH1A1 (0.59) HPGDMAPTRAB9AALDH1A1MAPK1
SCHEMBL9686546 0.80 SMN1; SMN2 (0.73) HPGDMAPTRAB9AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
CN-87108027-A Imidazopyridine and preparation method thereof 1988-06-08 CN disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed