SCHEMBL9685656

SCHEMBL9685656

[CH2]c1c(C)cccc1NC(=O)CO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 3/20 0.48
KMT2A Q03164 3/20 0.48
TP53 P04637 1/20 0.48
GAA P10253 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.47
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 2/20 0.45
HDAC11 Q96DB2 2/20 0.45
HDAC8 Q9BY41 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
HDAC9 Q9UKV0 2/20 0.45
HDAC5 Q9UQL6 2/20 0.45
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687479 0.86 HPGD (0.47) HPGDALDH1A1MAPK1KMT2ATP53
SCHEMBL9686240 0.85 CA1 (0.47) HPGDALDH1A1MAPK1KMT2ATP53
SCHEMBL9686302 0.83 MAPK1 (0.57) ALDH1A1MAPK1KMT2AGAAHDAC3
SCHEMBL5892350 0.82 HPGD (0.68) HPGDALDH1A1MAPK1ALOX12HDAC3
SCHEMBL9686605 0.80 ALDH1A1 (0.66) HPGDALDH1A1MAPK1KMT2AGAA
SCHEMBL9686546 0.80 SMN1; SMN2 (0.73) HPGDALDH1A1KMT2AGAARAB9A
SCHEMBL9685670 0.79 POLB (0.54) HPGDALDH1A1MAPK1KMT2ATP53
SCHEMBL9686399 0.77 ALDH1A1 (0.60) HPGDALDH1A1TP53GAAALOX15
SCHEMBL9685750 0.77 NPC1 (0.53) HPGDALDH1A1GAAALOX12RAB9A
SCHEMBL5839856 0.77 HPGD (0.49) HPGDALDH1A1MAPK1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP claimed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US claimed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP claimed
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed