Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686454 | 0.71 | FDPS (0.37) | AHCYFDPSDGAT1TYMPHDAC6 | |
| SCHEMBL9685043 | 0.66 | ADCY5 (0.47) | FDPSDGAT1ADORA3ADORA2AADORA1 | |
| SCHEMBL10172069 | 0.59 | AHCY (0.53) | AHCY | |
| SCHEMBL14037523 | 0.59 | P2RX7 (0.42) | AHCYTYMPHDAC6 | |
| SCHEMBL20691350 | 0.58 | TYMP (0.58) | AHCYTYMP | |
| SCHEMBL10171923 | 0.58 | PDE2A (0.42) | TYMP | |
| SCHEMBL5368535 | 0.58 | AHCY (0.58) | AHCY | |
| SCHEMBL5366317 | 0.58 | AHCY (0.52) | AHCYTYMP | |
| SCHEMBL9786779 | 0.58 | AHCY (0.71) | AHCYPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26382100 | 0.58 | AHCY (0.71) | AHCYPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468119-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |