Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687032 | 0.87 | BRD4 (0.36) | BRD4HTTTSHRPIK3CGCYP1B1 | |
| SCHEMBL9686626 | 0.81 | HDAC4 (0.41) | BRD4HTTTSHRPLK1PIK3CG | |
| SCHEMBL9832981 | 0.79 | HTT (0.49) | BRD4HTTTSHRPLK1PIK3CG | |
| SCHEMBL9831606 | 0.77 | PLK1 (0.45) | BRD4HTTTSHRPLK1PIK3CG | |
| SCHEMBL9831062 | 0.77 | HTT (0.44) | BRD4HTTTSHRPLK1ALDH1A1 | |
| SCHEMBL9872261 | 0.73 | NMT1 (0.37) | BRD4HTTTSHRPIK3CGALDH1A1 | |
| SCHEMBL9686487 | 0.73 | CYP1B1 (0.36) | CYP1B1 | |
| SCHEMBL9687722 | 0.72 | HDAC4 (0.39) | BRD4HTTTSHRPLK1PIK3CG | |
| SCHEMBL9687661 | 0.71 | BRD4 (0.54) | BRD4TSHRPIK3CGALDH1A1ALOX15 | |
| SCHEMBL9687801 | 0.67 | BRD4 (0.57) | BRD4TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |