Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686626 | 0.90 | HDAC4 (0.41) | HDAC4HDAC1HDAC6TSHRHTT | |
| SCHEMBL9687032 | 0.80 | BRD4 (0.36) | TSHRHTTPIK3CGSLC5A1SLC5A2 | |
| SCHEMBL9687661 | 0.77 | BRD4 (0.54) | HDAC1HDAC6TSHRPIK3CGBRD4 | |
| SCHEMBL4075188 | 0.75 | TSHR (0.38) | TSHRHTTPLK1CYP1A2CYP3A4 | |
| SCHEMBL9686469 | 0.73 | NMT1 (0.41) | HDAC4HDAC1HDAC6TSHRHTT | |
| SCHEMBL9423272 | 0.72 | SLC5A1 (0.38) | TSHRHTTPLK1CYP3A4CYP2D6 | |
| SCHEMBL9686613 | 0.72 | BRD4 (0.43) | TSHRHTTPIK3CGPLK1CYP1A2 | |
| SCHEMBL9685814 | 0.70 | TERT (0.44) | HDAC4HDAC1HDAC6TSHRSLC5A1 | |
| SCHEMBL9832981 | 0.68 | HTT (0.49) | TSHRHTTPIK3CGPLK1SLC5A1 | |
| SCHEMBL9686487 | 0.67 | CYP1B1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |