Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CALCA | P06881 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685904 | 0.85 | BRD4 (0.49) | BRD4ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL9687032 | 0.84 | BRD4 (0.36) | BRD4TSHRL3MBTL1PIK3CG | |
| SCHEMBL18497028 | 0.80 | BRD4 (0.62) | BRD4ALDH1A1ALOX15TSHRRXFP1 | |
| SCHEMBL5340711 | 0.78 | BRD4 (0.63) | BRD4ALDH1A1ALOX15TSHRRXFP1 | |
| SCHEMBL4075188 | 0.77 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL9687722 | 0.77 | HDAC4 (0.39) | BRD4TSHRL3MBTL1HDAC1HDAC6 | |
| SCHEMBL9686505 | 0.75 | BRD4 (0.45) | BRD4ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL9685821 | 0.74 | BRD4 (0.44) | BRD4ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL9686618 | 0.74 | PPOX (0.46) | BRD4ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL18581748 | 0.73 | BRD4 (0.55) | BRD4ALDH1A1ALOX15TSHRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |