Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486849 | 0.77 | MEN1 (0.63) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL30289323 | 0.74 | KMT2A (1.00) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL8844868 | 0.74 | KMT2A (1.00) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL9686097 | 0.70 | MEN1 (0.75) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL464739 | 0.70 | MEN1 (0.60) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL15400202 | 0.69 | MEN1 (0.59) | MEN1KMT2APDGFRBGABRA1GABRA5 | |
| Ro-24-7429 SCHEMBL29736766 | 0.68 | MEN1 (0.70) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL9737375 | 0.68 | MEN1 (0.60) | MEN1KMT2ACNR1NTSR1OPRK1 | |
| SCHEMBL7834014 | 0.66 | CCNE2 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27357401 | 0.65 | MEN1 (0.54) | MEN1KMT2ACNR1NTSR1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475231-A1 | Benzodiazepines | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |