Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435727 | 0.98 | HCAR2 (0.53) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL19435724 | 0.98 | HCAR2 (0.53) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL19435723 | 0.98 | HCAR2 (0.53) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL4913015 | 0.74 | RAB9A (0.56) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL4913013 | 0.74 | RAB9A (0.56) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL1862223 | 0.74 | HCAR2 (0.69) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL369705 | 0.74 | HCAR2 (0.69) | HCAR2LMNARAB9AKMT2AMEN1 | |
| Acetone SCHEMBL8093756 | 0.73 | HCAR2 (0.67) | HCAR2LMNARAB9AKMT2AMEN1 | |
| Acetone SCHEMBL8093753 | 0.73 | HCAR2 (0.67) | HCAR2LMNARAB9AKMT2AMEN1 | |
| SCHEMBL7207106 | 0.71 | SMN1; SMN2 (0.43) | HCAR2LMNARAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191989-B1 | ANTIBIOTIC ISOXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |