SCHEMBL369705

SCHEMBL369705

CC(=O)/C=C/c1cccs1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.69
LMNA P02545 3/20 0.60
ABCG2 Q9UNQ0 2/20 0.57
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 1/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
HTT P42858 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
PSMD14 O00487 1/20 0.53
TP53 P04637 1/20 0.53
GLA P06280 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1862223 1.00 HCAR2 (0.69) HCAR2LMNAABCG2SMN1; SMN2MAPT
Acetone SCHEMBL8093753 0.98 HCAR2 (0.67) HCAR2LMNAABCG2SMN1; SMN2MAPT
Acetone SCHEMBL8093756 0.98 HCAR2 (0.67) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL5598741 0.83 HCAR2 (0.74) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL5598744 0.83 HCAR2 (0.74) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL143282 0.82 HCAR2 (1.00) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL600082 0.82 HCAR2 (1.00) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL4197243 0.82 HCAR2 (0.71) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL1086015 0.82 HCAR2 (0.71) HCAR2LMNAABCG2SMN1; SMN2MAPT
SCHEMBL24728234 0.80 HCAR2 (0.58) HCAR2LMNAABCG2SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104860854-A Method for synthesizing beta-thiocarbonyl compound by taking Bunte salt as sulfur source UNIV NANJING SCIENCE & TECH 2015-08-26 CN claimed
EP-4727923-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIV GEORGIA (US) 2026-04-09 US disclosed
US-12519071-B2 Structure containing Sn layer or Sn alloy layer ISHIHARA CHEMICAL CO., LTD. (JP) 2026-01-06 US disclosed
EP-3238861-B1 SOLDER MATERIAL, SOLDER PASTE, FOAM SOLDER, FLUX COATING MATERIAL SENJU METAL INDUSTRY CO (JP) 2025-08-27 EP disclosed
US-12388035-B2 Structure comprising under barrier metal and solder layer, and method for producing structure ISHIHARA CHEMICAL CO., LTD. (JP) 2025-08-12 US disclosed
WO-2024258904-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed
US-20240258255-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE ISHIHARA CHEMICAL CO., LTD. (JP) 2024-08-01 US disclosed
EP-4350748-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE Ishihara Chemical Co., Ltd (JP) 2024-04-10 EP disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 US disclosed
US-7326423-B2 Copolymerizable azo compounds and articles containing them ADVANCED MEDICAL OPTICS, INC. (US) 2008-02-05 US disclosed
US-7179308-B2 Ethylenically-unsaturated blue anthraquinone dyes EASTMAN CHEMICAL COMPANY (US) 2007-02-20 US disclosed
US-7172634-B2 Ethylenically-unsaturated blue anthraquinone dyes EASTMAN CHEMICAL COMPANY (US) 2007-02-06 US disclosed
EP-1026151-B1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides DOW AGROSCIENCES LLC (US) 2005-03-16 EP disclosed
WO-2004018462-A1 QUINAZOLINONE DERIVATIVES CELLTECH R & D LIMITED (GB) 2004-03-04 WO disclosed
EP-1026151-A1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 2000-08-09 EP disclosed
US-6063956-A APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED ROHM AND HAAS COMPANY (US) 2000-05-16 US disclosed
EP-0316790-B1 RHODANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE NISSHIN FLOUR MILLING CO., LTD. (JP) 1993-08-11 EP disclosed
US-4897406-A CHEMICAL MEDIATOR INHIBITORS INCLUDING LEUKOTRIENES; ANTIALLERGENS; BRONCHODILATOR AND ANTIICHEMIC AGENTS NISSHIN FLOUR MILLING CO., LTD. (JP) 1990-01-30 US disclosed
EP-0316790-A1 Rhodanine derivatives, a process for their preparation, pharmaceutical compositions and their use NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA CD47, SLC11A2, G6PD HCAR2 1623/4885LMNA 297/4885ABCG2 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.