Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984088 | 0.80 | MT-CO2 (0.45) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9875354 | 0.79 | MT-CO2 (0.44) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9875746 | 0.76 | MT-CO2 (0.41) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9876109 | 0.76 | MT-CO2 (0.41) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9875536 | 0.76 | MT-CO2 (0.55) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9874997 | 0.75 | MT-CO2 (0.54) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL10673681 | 0.73 | MT-CO2 (0.55) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9875636 | 0.73 | TAS2R14 (0.52) | MT-CO2KMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL9875471 | 0.72 | MT-CO2 (0.54) | MT-CO2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3220136 | 0.72 | PDE4B (0.45) | MT-CO2KMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273176-B1 | FUSED HETEROCYCLIC TETRAHYDROAMINOQUINOLINOLS AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0273176-A2 | Fused heterocyclic tetrahydroaminoquinolinols and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4753950-A | MEMORY ENHANCEMENT, ALZHEIMER*S DISEASE | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-28 | — | — | US | disclosed |