SCHEMBL9687212

SCHEMBL9687212

NNC(=O)c1c(Cl)ccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
GAA P10253 4/20 0.49
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
CYP2A6 P11509 1/20 0.46
MITF O75030 1/20 0.45
NCOA1 Q15788 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NCOA3 Q9Y6Q9 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
OGG1 O15527 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775545 0.82 GAA (0.51) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL5274333 0.82 NCEH1 (0.44) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL856182 0.81 MAPT (0.50) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL1639535 0.81 ALOX15 (0.55) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL7598995 0.79 GAA (0.49) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL6609007 0.78 ALDH1A1 (0.54) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL28069317 0.78 ALDH1A1 (0.59) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL3146455 0.78 HSD17B10 (0.59) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL5480836 0.78 WDR5 (0.56) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL9471969 0.77 MAPT (0.47) MAPTGAAALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104442-A Cereals HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
EP-0470489-A1 4,5,6,7-Tetrahydro-3-aryl-indazoles, process for their preparation and their use as herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-12 EP disclosed
US-4259235-A REDUCTION OF PLANT GROWTH HEIGHT BASF AKTIENGESELLSCHAFT (DE) 1981-03-31 US disclosed
US-3944556-A PHOTOCONDUCTOR, FLUORESCENT, PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1976-03-16 US disclosed