Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688265 | 0.82 | KMT2A (0.50) | MAPTKMT2AMEN1 | |
| SCHEMBL9027351 | 0.80 | SMN1; SMN2 (0.44) | MAPTKDM4EAPAF1POLBRECQL | |
| SCHEMBL9026342 | 0.78 | MAPT (0.39) | MAPTKDM4EAPAF1POLBRECQL | |
| SCHEMBL9025829 | 0.72 | MAPT (0.42) | MAPTKDM4EAPAF1POLBRECQL | |
| SCHEMBL9027577 | 0.72 | MAPT (0.41) | MAPTKDM4EAPAF1POLBRECQL | |
| SCHEMBL9164176 | 0.71 | GPR84 (0.43) | MAPTKDM4EAPAF1POLBRECQL | |
| SCHEMBL9688037 | 0.71 | TSHR (0.49) | MAPTKDM4EPOLBKMT2A | |
| SCHEMBL9688033 | 0.71 | HTT (0.49) | KDM4EPOLBRECQLL3MBTL1GAA | |
| SCHEMBL9689043 | 0.70 | HPGD (0.39) | MAPTKMT2AMEN1PKM | |
| SCHEMBL9025880 | 0.70 | HTR2A (0.39) | MAPTKDM4EAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |