Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689043 | 0.80 | HPGD (0.39) | TSHRSMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL9687941 | 0.79 | EZH2 (0.40) | SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9688033 | 0.78 | HTT (0.49) | TSHRSMN1; SMN2KMT2APOLBRAB9A | |
| SCHEMBL9687454 | 0.75 | MEN1 (0.39) | KMT2AMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9687392 | 0.75 | CYP1A2 (0.46) | TSHRSMN1; SMN2KMT2APOLBPTGS2 | |
| SCHEMBL9687391 | 0.72 | HPGD (0.39) | TSHRSMN1; SMN2KMT2APOLBMAPT | |
| SCHEMBL9687431 | 0.71 | MAPT (0.38) | KMT2APOLBMAPTKDM4E | |
| SCHEMBL9280239 | 0.71 | RXFP1 (0.45) | TSHRSMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL9027351 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2APOLBRAB9AMAPT | |
| SCHEMBL9278822 | 0.69 | RAB9A (0.46) | TSHRSMN1; SMN2KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |