Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687941 | 0.82 | EZH2 (0.40) | HPGDKMT2AMEN1ROCK2NPC1 | |
| SCHEMBL9688037 | 0.80 | TSHR (0.49) | KMT2AALDH1A1MAPTTSHRRAB9A | |
| SCHEMBL9688033 | 0.79 | HTT (0.49) | HPGDKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9687391 | 0.78 | HPGD (0.39) | HPGDKMT2AMEN1ROCK2ROCK1 | |
| SCHEMBL9687454 | 0.78 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL9687392 | 0.77 | CYP1A2 (0.46) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9280239 | 0.74 | RXFP1 (0.45) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL9687611 | 0.74 | KMT2A (0.48) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9278822 | 0.72 | RAB9A (0.46) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9687431 | 0.70 | MAPT (0.38) | KMT2AMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |