Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687941 | 0.81 | EZH2 (0.40) | HTTHPGDSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9687454 | 0.80 | MEN1 (0.39) | HTTRECQLALDH1A1KMT2AKDM4E | |
| SCHEMBL9687392 | 0.80 | CYP1A2 (0.46) | GAANPSR1ALDH1A1HPGDPOLB | |
| SCHEMBL9688037 | 0.78 | TSHR (0.49) | ALDH1A1POLBSMN1; SMN2TSHRLMNA | |
| SCHEMBL9687391 | 0.73 | HPGD (0.39) | HTTGAANPSR1ALDH1A1HPGD | |
| SCHEMBL13988483 | 0.65 | GAA (0.65) | HTTGAAL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL8326064 | 0.65 | GAA (1.00) | HTTGAARECQLL3MBTL1NPSR1 | |
| SCHEMBL13955307 | 0.65 | RECQL (0.66) | HTTGAARECQLL3MBTL1NPSR1 | |
| SCHEMBL13774773 | 0.64 | L3MBTL1 (0.73) | HTTGAARECQLL3MBTL1ALDH1A1 | |
| SCHEMBL10311689 | 0.64 | PKM (0.73) | HTTRECQLL3MBTL1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |