Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687941 | 0.72 | EZH2 (0.40) | MEN1KMT2AHTTSMN1; SMN2NPC1 | |
| SCHEMBL14758395 | 0.67 | ALDH1A1 (0.81) | HPGDSPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9653806 | 0.67 | MEN1 (0.85) | HPGDSPOLBPKMMEN1KMT2A | |
| SCHEMBL18541844 | 0.67 | ALDH1A1 (0.68) | HPGDSPOLBPKMMEN1KMT2A | |
| SCHEMBL16026545 | 0.67 | PKM (0.74) | HPGDSPOLBPKMMEN1KMT2A | |
| SCHEMBL27829788 | 0.67 | AKR1C3 (0.83) | HPGDSPOLBPKMMEN1KMT2A | |
| SCHEMBL3252759 | 0.66 | PKM (0.78) | PKMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9687454 | 0.66 | MEN1 (0.39) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL7793932 | 0.65 | AKR1C3 (0.68) | HPGDSPOLBPKMMEN1KMT2A | |
| SCHEMBL3904994 | 0.65 | KMT2A (0.68) | HPGDSPOLBPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |