Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687366 | 0.92 | PDE2A (0.41) | MEN1KMT2APDE2AALDH1A1 | |
| SCHEMBL9687392 | 0.90 | CYP1A2 (0.46) | MEN1KMT2ATRPV1HSD17B10ALDH1A1 | |
| SCHEMBL9686898 | 0.88 | HMGCR (0.35) | MEN1KMT2ATDP1RECQLALDH1A1 | |
| SCHEMBL9687941 | 0.83 | EZH2 (0.40) | MEN1KMT2AEZH2KDM4EHTT | |
| SCHEMBL9164713 | 0.83 | MMP13 (0.48) | ALDH1A1MAPTKDM4EHTT | |
| SCHEMBL9688033 | 0.80 | HTT (0.49) | MEN1KMT2AHSD17B10RECQLALDH1A1 | |
| SCHEMBL9687409 | 0.78 | LMNA (0.43) | MEN1KMT2AMAPTHTT | |
| SCHEMBL9687391 | 0.77 | HPGD (0.39) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9686935 | 0.76 | CNR1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL9688037 | 0.75 | TSHR (0.49) | KMT2AHSD17B10ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |