SCHEMBL9687531

SCHEMBL9687531

C=CC(Cc1ccccc1)(C(=O)OC)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTPN1 P18031 4/20 0.47
PTPRB P23467 3/20 0.47
PTPN2 P17706 2/20 0.47
PTPRA P18433 1/20 0.47
KCNN4 O15554 1/20 0.44
MMP8 P22894 3/20 0.43
RECQL P46063 2/20 0.43
CTRB1 P17538 1/20 0.41
SRC P12931 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPRC P08575 1/20 0.40
PTPRG P23470 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9687488 0.84 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19MMP8
SCHEMBL6834512 0.81 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19MMP8
SCHEMBL9686984 0.80 ALDH1A1 (0.47) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL24872640 0.78 PTPRB (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL11533573 0.77 CTRB1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL28420568 0.77 PTPRB (0.54) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL9686667 0.77 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19MMP8
SCHEMBL11175367 0.77 PTPRB (0.69) ALDH1A1PTPN1PTPRBPTPN2PTPRA
SCHEMBL8537306 0.75 ALDH1A1 (0.45) ALDH1A1CYP3A4CYP2C9CYP2C19MMP8
SCHEMBL21811199 0.75 MMP8 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147952-A PROCESS FOR PRODUCING MACROMOLECULAR MONOMER TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-09-15 US disclosed