Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfonet SCHEMBL10627756 | 0.98 | MMP2 (0.41) | MMP2MMP9CA12CA1CA2 | |
| Malonic Acid SCHEMBL2174031 | 0.79 | CA4 (0.48) | MMP2MMP9CA12CA1CA2 | |
| Fosfonet SCHEMBL10627749 | 0.78 | MEN1 (0.54) | MMP2MMP9CA12CA1CA2 | |
| Medronic Acid SCHEMBL10617929 | 0.76 | MMP2 (0.50) | MMP2MMP9CA12CA1CA2 | |
| SCHEMBL9563827 | 0.76 | THRB (0.50) | MMP2MMP9CA12CA1CA2 | |
| Medronic Acid SCHEMBL832868 | 0.76 | MMP2 (0.50) | MMP2MMP9CA12CA1CA2 | |
| Medronic Acid SCHEMBL9838135 | 0.76 | MMP2 (0.50) | MMP2MMP9CA12CA1CA2 | |
| Oxalic Acid SCHEMBL29422639 | 0.75 | MEN1 (0.56) | MMP2MMP9CA12CA1CA2 | |
| Oxalic Acid SCHEMBL4859 | 0.75 | MEN1 (0.56) | MMP2MMP9CA12CA1CA2 | |
| Oxalic Acid SCHEMBL965059 | 0.75 | MEN1 (0.56) | MMP2MMP9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318464-B1 | ANTITUMOR PLATINUM COMPLEXES | Bristol-Myers Squibb Company (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0318464-A2 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1989-05-31 | — | — | EP | disclosed |
| EP-0306605-A1 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4594418-A | A 1,2-cyclohexane platinum complex | BRISTOL-MYERS COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| US-4562275-A | ANTICARCINOGENIC AGENTS | BRISTOL-MYERS CO. (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0155705-A2 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1985-09-25 | — | — | EP | disclosed |