Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688802 | 0.93 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| Hydrochloric Acid SCHEMBL9688696 | 0.91 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| Hydrochloric Acid SCHEMBL9688707 | 0.91 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| SCHEMBL9687538 | 0.90 | MTNR1A (0.57) | MTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL9687679 | 0.90 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| SCHEMBL10474646 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| SCHEMBL9688376 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| SCHEMBL10377880 | 0.80 | DPP7 (0.49) | MTNR1AMTNR1BALDH1A1GAA | |
| SCHEMBL9688248 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| Hydrochloric Acid SCHEMBL10377647 | 0.79 | DPP7 (0.48) | MTNR1AMTNR1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279125-B1 | TETRAHYDROPYRIDO(1,2-A)INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1992-04-29 | — | — | EP | claimed |
| EP-0279125-A1 | Tetrahydropyrido(1,2-a)indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-08-24 | — | — | EP | claimed |
| EP-0279125-B1 | TETRAHYDROPYRIDO(1,2-A)INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1992-04-29 | — | — | EP | disclosed |
| US-4968699-A | CENTRAL NERVOUS SYSTEM; ANTIISCHEMIC AND ANTIHYPOXIC AGENTS; ACTIVE AGAINST CEREBRAL OXYGEN DEFICIENCY | BEECHAM-WUELFING GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0279125-A1 | Tetrahydropyrido(1,2-a)indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-08-24 | — | — | EP | disclosed |