Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688376 | 0.94 | MTNR1A (0.55) | MTNR1AMTNR1BKDM4EGMNNALDH1A1 | |
| SCHEMBL9687538 | 0.89 | MTNR1A (0.57) | MTNR1AMTNR1BALDH1A1LMNAHPGD | |
| SCHEMBL9687575 | 0.85 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1HPGDTERT | |
| SCHEMBL9688248 | 0.84 | MTNR1A (0.55) | MTNR1AMTNR1BKDM4EGMNNALDH1A1 | |
| SCHEMBL9688587 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1BKDM4EGMNNALDH1A1 | |
| SCHEMBL9688802 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1CYP2D6HPGD | |
| Hydrochloric Acid SCHEMBL9688826 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BKDM4EGMNNALDH1A1 | |
| Hydrochloric Acid SCHEMBL9688696 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1CYP2D6HPGD | |
| Hydrochloric Acid SCHEMBL9688707 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1CYP2D6HPGD | |
| SCHEMBL9687679 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968699-A | CENTRAL NERVOUS SYSTEM; ANTIISCHEMIC AND ANTIHYPOXIC AGENTS; ACTIVE AGAINST CEREBRAL OXYGEN DEFICIENCY | BEECHAM-WUELFING GMBH & CO. (DE) | 1990-11-06 | — | — | US | disclosed |