Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9688642 | 0.99 | MTNR1A (0.45) | MTNR1AMTNR1BESRRGCD274TP53 | |
| SCHEMBL9689411 | 0.89 | NPC1 (0.45) | MTNR1AMTNR1BTP53MAPTPOLB | |
| Hydrochloric Acid SCHEMBL9688101 | 0.88 | NPC1 (0.44) | MTNR1AMTNR1BTP53MAPTPOLB | |
| SCHEMBL9687666 | 0.87 | NAMPT (0.46) | MTNR1AMTNR1B | |
| SCHEMBL9688802 | 0.86 | MTNR1A (0.50) | MTNR1AMTNR1BCYP2D6 | |
| SCHEMBL9688621 | 0.86 | SMN1; SMN2 (0.52) | MTNR1AMTNR1BTP53MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9687465 | 0.85 | ACHE (0.47) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9687471 | 0.85 | ACHE (0.47) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9688696 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BCYP2D6 | |
| Hydrochloric Acid SCHEMBL9688707 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279125-B1 | TETRAHYDROPYRIDO(1,2-A)INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1992-04-29 | — | — | EP | claimed |
| EP-0279125-A1 | Tetrahydropyrido(1,2-a)indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-08-24 | — | — | EP | claimed |