Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9687465 | 0.98 | ACHE (0.47) | NAMPTMTNR1AMTNR1BACHEPTGDR2 | |
| Hydrochloric Acid SCHEMBL9687471 | 0.98 | ACHE (0.47) | NAMPTMTNR1AMTNR1BACHEPTGDR2 | |
| SCHEMBL9687679 | 0.87 | MTNR1A (0.50) | MTNR1AMTNR1BPTGDR2ALDH1A1GAA | |
| SCHEMBL9687600 | 0.87 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9688642 | 0.86 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL9688621 | 0.83 | SMN1; SMN2 (0.52) | MTNR1AMTNR1BALDH1A1GAAKMT2A | |
| SCHEMBL9687497 | 0.83 | NAMPT (0.43) | NAMPTACHEALDH1A1GAAHPGD | |
| SCHEMBL10572700 | 0.82 | MTNR1A (0.43) | NAMPTMTNR1AMTNR1B | |
| SCHEMBL10377745 | 0.81 | HTR6 (0.42) | MTNR1AMTNR1BPTGDR2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10644126 | 0.81 | MTNR1A (0.42) | NAMPTMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279125-B1 | TETRAHYDROPYRIDO(1,2-A)INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1992-04-29 | — | — | EP | claimed |
| EP-0279125-A1 | Tetrahydropyrido(1,2-a)indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-08-24 | — | — | EP | claimed |