Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.47 |
| ▸ | NOS3 | P29474 | 4/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687039 | 0.82 | NOS2 (0.44) | NOS2NOS3NOS1 | |
| SCHEMBL4987971 | 0.76 | NOS2 (0.42) | NOS2NOS3NOS1 | |
| SCHEMBL9686513 | 0.72 | NOS2 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL9536189 | 0.71 | NOS2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL22068695 | 0.71 | NOS2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL9686545 | 0.71 | MAPT (0.49) | NOS2NOS3NOS1 | |
| SCHEMBL9387184 | 0.70 | GAA (0.40) | NOS2NOS3 | |
| SCHEMBL4986132 | 0.70 | NOS2 (0.42) | NOS2NOS3NOS1 | |
| SCHEMBL3264472 | 0.69 | NOS2 (0.52) | NOS2NOS3NOS1 | |
| SCHEMBL25256924 | 0.69 | NOS2 (0.41) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295742-B1 | NOVEL N-(4-PIPERIDINYL) BICYCLIC CONDENSED 2-IMIDAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0295742-A1 | Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |