Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687108 | 0.83 | SMPD3 (0.33) | MCHR1DRD2 | |
| SCHEMBL9688424 | 0.76 | POLB (0.40) | PDE4B | |
| SCHEMBL9687813 | 0.70 | ABCB1 (0.42) | DRD2 | |
| SCHEMBL9688429 | 0.70 | OPRD1 (0.40) | L3MBTL1DRD2 | |
| SCHEMBL23343275 | 0.69 | DRD2 (0.36) | DRD2 | |
| SCHEMBL5522770 | 0.68 | NFKB1 (0.51) | L3MBTL1DRD2ALOX15 | |
| SCHEMBL5529209 | 0.68 | NFKB1 (0.51) | L3MBTL1DRD2ALOX15 | |
| SCHEMBL5529736 | 0.68 | NFKB1 (0.51) | L3MBTL1DRD2ALOX15 | |
| SCHEMBL9686535 | 0.67 | AKR1C3 (0.43) | — | |
| SCHEMBL15004196 | 0.66 | DRD2 (0.47) | L3MBTL1DRD2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |