SCHEMBL9858415

SCHEMBL9858415

C=CC(C)(C)c1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
ACHE P22303 4/20 0.40
TDP1 Q9NUW8 1/20 0.40
ATM Q13315 2/20 0.38
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAPT P10636 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA5A P35218 1/20 0.34
CYP19A1 P11511 1/20 0.33
CYP2A6 P11509 1/20 0.33
TGM2 P21980 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CA7 P43166 1/20 0.32
MLYCD O95822 1/20 0.31
KIF11 P52732 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858671 0.82 TSHR (0.48) TSHRACHETDP1NPC1RAB9A
SCHEMBL5682958 0.80
SCHEMBL9163519 0.79 TSHR (0.50) TSHRACHETDP1ATMNPC1
SCHEMBL24278474 0.78 RAB9A (0.37) ACHENPC1RAB9AMAPTCYP19A1
SCHEMBL9790116 0.78 ESR1 (0.54) TSHRNPC1RAB9AMAPTCA1
SCHEMBL24277963 0.78 TGM2 (0.41) TSHRTGM2ALDH1A1KIF11
SCHEMBL4969374 0.77 TSHR (0.55) TSHRACHETDP1ATMNPC1
SCHEMBL737574 0.77 MAPK1 (0.44) TSHRMAPTALDH1A1
SCHEMBL2247665 0.76 TSHR (0.48) TSHRACHETDP1ATMNPC1
SCHEMBL23747059 0.73 KIF11 (0.41) TSHRNPC1RAB9AMAPTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291849-B1 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed
EP-0219092-B1 PROCESS FOR PREPARING ALKENYLAROMATIC COMPOUNDS BASF Aktiengesellschaft (DE) 1989-10-04 EP disclosed
US-4837201-A 4-Methyl-4-phenyl-1-pentanals, their preparation and their use as scents BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0291849-A2 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed
US-4709109-A Preparation of alkenylaromatics BASF AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed