Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687697 | 0.89 | AOC3 (0.39) | AOC3HDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL21739867 | 0.83 | AOC3 (0.41) | AOC3HDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL9688872 | 0.83 | AOC3 (0.37) | AOC3HDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL9687417 | 0.79 | AOC3 (0.41) | AOC3SLC6A4SLC6A2 | |
| SCHEMBL9248072 | 0.79 | ACHE (0.41) | AOC3ACHE | |
| SCHEMBL10442326 | 0.78 | AOC3 (0.46) | AOC3HDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL9688011 | 0.78 | ADRB1 (0.53) | ACHE | |
| SCHEMBL9686706 | 0.78 | IDO1 (0.39) | IDO1TDO2SLC6A4SLC6A2 | |
| SCHEMBL9688924 | 0.78 | ADRB1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL6001272 | 0.76 | AOC3 (0.45) | AOC3HDAC4HDAC7HDAC5IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |