Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9024965 | 0.99 | HTR7 (0.41) | HTR7METAP1GPBAR1HSP90AA1MITF | |
| SCHEMBL9445145 | 0.84 | PTGS2 (0.39) | HTR7METAP1HSP90AA1MITFPTGS1 | |
| SCHEMBL9024867 | 0.83 | HTR7 (0.43) | HTR7GPBAR1PTGS1RORCNPC1 | |
| Hydrochloric Acid SCHEMBL9445152 | 0.83 | HSP90AA1 (0.39) | HTR7METAP1HSP90AA1MITFPTGS1 | |
| SCHEMBL9023952 | 0.81 | HTR7 (0.41) | HTR7GPBAR1PTGS1RORCNPC1 | |
| SCHEMBL9689733 | 0.78 | CYP3A4 (0.52) | HTR7NPC1RAB9A | |
| SCHEMBL9445144 | 0.77 | HTR7 (0.41) | HTR7GPBAR1PTGS1RORCNPC1 | |
| SCHEMBL9445175 | 0.74 | HTR2C (0.51) | HTR7HTR1A | |
| Fumaric Acid SCHEMBL9445154 | 0.72 | CYP3A4 (0.46) | HTR7NPC1RAB9A | |
| Maleic Acid SCHEMBL9445151 | 0.72 | CYP3A4 (0.46) | HTR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |