Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370567 | 0.80 | EPHX2 (0.50) | HTR2CPLD1 | |
| SCHEMBL9688903 | 0.72 | HTR2C (0.42) | HTR2C | |
| SCHEMBL9688689 | 0.71 | CYP2D6 (0.48) | HTR2C | |
| SCHEMBL27564193 | 0.70 | HTR2C (0.45) | HTR2CHTR2B | |
| SCHEMBL13354907 | 0.70 | HRH4 (0.45) | HTR2CPLD1ADRB2NCF1 | |
| SCHEMBL14328422 | 0.70 | HTR2C (0.41) | HTR2CPLD1ADRB2NCF1 | |
| SCHEMBL31651827 | 0.70 | HTR3E (0.49) | NCF1 | |
| SCHEMBL4727172 | 0.68 | ADRB2 (0.38) | HTR2CPLD1ADRB2NCF1 | |
| SCHEMBL194495 | 0.67 | NCF1 (0.42) | HTR2CPLD1ADRB2NCF1 | |
| SCHEMBL20139855 | 0.67 | ROCK2 (0.45) | HTR2CPLD1ADRB2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |