Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP14 | P50281 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393977 | 0.81 | KMT2A (0.55) | MMP2MMP9MMP14KMT2ACA2 | |
| SCHEMBL23449 | 0.80 | MMP2 (0.44) | MMP2MMP9MMP14KMT2AMMP7 | |
| SCHEMBL27865463 | 0.79 | KMT2A (0.53) | MMP2MMP9MMP14KMT2ACA2 | |
| SCHEMBL28588755 | 0.78 | MMP2 (0.52) | MMP2MMP9MMP14KMT2AMAPT | |
| SCHEMBL1008446 | 0.76 | MMP2 (0.48) | MMP2MMP9MMP14KMT2AMMP7 | |
| SCHEMBL7295678 | 0.75 | CA2 (0.33) | CA2CA9 | |
| SCHEMBL17718484 | 0.74 | MAPK1 (0.53) | MMP2MMP9MMP14KMT2ACA2 | |
| SCHEMBL9686680 | 0.73 | ALPL (0.42) | MMP2MMP9MMP14MAPTMMP7 | |
| SCHEMBL7297750 | 0.71 | ALPL (0.43) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL23650 | 0.71 | MMP2 (0.40) | MMP2MMP9MMP14MMP7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |