Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016435 | 0.76 | — | — | |
| SCHEMBL12827565 | 0.73 | GRM5 (0.37) | NPC1GAAMAPK1RAB9A | |
| SCHEMBL6901677 | 0.73 | NPC1 (0.46) | NPC1GAAMAPK1RAB9A | |
| SCHEMBL9688115 | 0.73 | ALDH1A1 (0.32) | GAA | |
| SCHEMBL2175079 | 0.71 | ALDH1A1 (0.48) | NPC1GAARAB9A | |
| SCHEMBL10571843 | 0.71 | KMT2A (0.33) | NPC1GAAMAPK1RAB9A | |
| SCHEMBL6174246 | 0.70 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL10987975 | 0.70 | ALDH1A1 (0.47) | NPC1GAARAB9A | |
| SCHEMBL15890632 | 0.68 | HTT (0.34) | — | |
| SCHEMBL17480642 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-5124450-A | Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst | AKZO N.V. (NL) | 1992-06-23 | — | — | US | disclosed |
| EP-0481366-A1 | Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles | Akzo Nobel N.V. (NL) | 1992-04-22 | — | — | EP | disclosed |
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | disclosed |