Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.47 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169606 | 0.93 | RAB9A (0.47) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9165874 | 0.91 | HSD17B1 (0.44) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9254097 | 0.90 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9173628 | 0.90 | RAB9A (0.45) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9166749 | 0.89 | RAB9A (0.41) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9168612 | 0.87 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9168862 | 0.86 | NPC1 (0.39) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9166552 | 0.86 | KDR (0.48) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9172844 | 0.86 | HSD17B1 (0.46) | NPC1RAB9AKMT2AMEN1RXFP1 | |
| SCHEMBL9173884 | 0.84 | RAB9A (0.40) | NPC1RAB9AKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503099-A1 | PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |