Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9445168 | 0.99 | ACHE (0.43) | ACHEDCTPP1NR4A2HTR1ASIGMAR1 | |
| SCHEMBL9688292 | 0.89 | METAP1 (0.41) | DCTPP1HTR1ASIGMAR1HDAC1HDAC6 | |
| SCHEMBL9689848 | 0.89 | NR4A2 (0.41) | DCTPP1NR4A2HTR1ASIGMAR1USP2 | |
| SCHEMBL9445139 | 0.88 | HDAC1 (0.41) | ACHEDCTPP1NR4A2HTR1AHDAC1 | |
| SCHEMBL9024259 | 0.88 | ADRA2A (0.43) | DCTPP1HTR1ASIGMAR1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9024275 | 0.88 | NR4A2 (0.41) | DCTPP1NR4A2HTR1AUSP2ADORA2A | |
| Hydrochloric Acid SCHEMBL9445255 | 0.87 | METAP1 (0.41) | DCTPP1HTR1ASIGMAR1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL9445252 | 0.87 | METAP1 (0.41) | DCTPP1HTR1ASIGMAR1HDAC1HDAC6 | |
| SCHEMBL9025330 | 0.80 | DRD2 (0.41) | DCTPP1HTR1ASIGMAR1 | |
| SCHEMBL9445210 | 0.80 | DCTPP1 (0.39) | DCTPP1HTR1AADORA2AADORA1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |