Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761734 | 0.80 | CA1 (0.61) | CA1CA2HPGDALDH1A1LMNA | |
| SCHEMBL15761720 | 0.79 | CA1 (0.60) | CA1CA2HPGDALDH1A1NPSR1 | |
| SCHEMBL15761732 | 0.79 | CA1 (0.60) | CA1CA2HPGDALDH1A1HTT | |
| SCHEMBL8033332 | 0.77 | MEN1 (0.54) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL6889611 | 0.77 | KDM4E (0.58) | CA1CA2HPGDALDH1A1KMT2A | |
| SCHEMBL2204779 | 0.76 | LMNA (0.59) | HPGDALDH1A1HTTLMNAKMT2A | |
| SCHEMBL19910593 | 0.76 | ALDH1A1 (0.60) | CA1CA2HPGDALDH1A1HTT | |
| SCHEMBL20183509 | 0.76 | CA1 (0.56) | CA1CA2HPGDALDH1A1HTT | |
| SCHEMBL8619629 | 0.75 | MAPK1 (0.60) | HPGDALDH1A1HTTNPSR1LMNA | |
| SCHEMBL6120695 | 0.75 | CA1 (0.88) | CA1CA2HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |