Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535606 | 0.88 | ALDH1A1 (0.64) | MEN1KMT2ALMNAMAPK1SSTR3 | |
| SCHEMBL8039815 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2ALMNASSTR3ALDH1A1 | |
| SCHEMBL8033450 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2ALMNASSTR3ALDH1A1 | |
| SCHEMBL8038721 | 0.84 | MEN1 (0.47) | MEN1KMT2ALMNAMAPK1SSTR3 | |
| SCHEMBL4539438 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2ALMNAMAPK1SSTR3 | |
| SCHEMBL4542148 | 0.77 | LMNA (0.53) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9688877 | 0.77 | CA1 (0.56) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL8041888 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8033328 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9402456 | 0.73 | HDAC8 (0.69) | MEN1KMT2AALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |