Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164648 | 0.68 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9688130 | 0.68 | LMNA (0.43) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9686909 | 0.67 | KMT2A (0.46) | DCTPP1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27739890 | 0.67 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6414178 | 0.67 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL19561830 | 0.67 | ALDH1A1 (0.73) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL4319359 | 0.66 | KMT2A (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8321177 | 0.66 | KMT2A (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL27918226 | 0.66 | KMT2A (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6493236 | 0.66 | KDM4E (0.57) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |