Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164648 | 0.90 | KMT2A (0.47) | KMT2AMEN1ALDH1A1THRBMAPT | |
| SCHEMBL9688018 | 0.80 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9686788 | 0.75 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9280239 | 0.69 | RXFP1 (0.45) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9164713 | 0.67 | MMP13 (0.48) | ALDH1A1LMNAMAPT | |
| SCHEMBL9689051 | 0.67 | DCTPP1 (0.50) | KMT2AMEN1DCTPP1ALDH1A1LMNA | |
| SCHEMBL14224740 | 0.67 | LMNA (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL14197088 | 0.67 | KMT2A (0.59) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9688086 | 0.67 | HSD17B2 (0.46) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL27739890 | 0.67 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |