Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691055 | 0.85 | HSD11B1 (0.45) | MAPTTP53POLBNPC1RAB9A | |
| SCHEMBL9690834 | 0.85 | PDE2A (0.46) | POLBNPC1RAB9ASMN1; SMN2GABRG2 | |
| SCHEMBL27438824 | 0.82 | DPP4 (0.38) | MAPTTP53POLBNPC1RAB9A | |
| SCHEMBL1664963 | 0.81 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ASMN1; SMN2CYP17A1 | |
| SCHEMBL9691041 | 0.80 | RAB9A (0.36) | MAPTTP53POLBNPC1RAB9A | |
| SCHEMBL9691024 | 0.80 | PDE2A (0.38) | MAPTTP53POLBCYP17A1CYP1A2 | |
| SCHEMBL27351162 | 0.74 | DPP4 (0.36) | NPC1RAB9ASMN1; SMN2PDE2APDE10A | |
| SCHEMBL9690728 | 0.74 | RXFP1 (0.46) | MAPTTP53POLBNPC1RAB9A | |
| SCHEMBL24121997 | 0.74 | RXFP1 (0.38) | SMN1; SMN2CYP17A1CYP1A2GABRG2GABRB3 | |
| SCHEMBL9691174 | 0.73 | CYP17A1 (0.49) | MAPTTP53POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |