Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE6A | P16499 | 1/20 | 0.35 |
| ▸ | PDE6G | P18545 | 1/20 | 0.35 |
| ▸ | PDE6B | P35913 | 1/20 | 0.35 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690834 | 0.88 | PDE2A (0.46) | PDE2APDE10AHSD11B1DCTPP1POLB | |
| SCHEMBL9689162 | 0.80 | MAPT (0.47) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL9691055 | 0.76 | HSD11B1 (0.45) | PDE10AHSD11B1DCTPP1CYP17A1TP53 | |
| SCHEMBL27438824 | 0.72 | DPP4 (0.38) | CYP17A1TP53POLBMAPTGABRG2 | |
| SCHEMBL27351162 | 0.71 | DPP4 (0.36) | PDE2APDE10AHSD11B1 | |
| SCHEMBL1664963 | 0.71 | SMN1; SMN2 (0.50) | CYP17A1MAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL9691041 | 0.71 | RAB9A (0.36) | PDE2AHSD11B1CYP17A1TP53POLB | |
| SCHEMBL9691174 | 0.71 | CYP17A1 (0.49) | DCTPP1CYP17A1TP53POLBMAPT | |
| SCHEMBL9689092 | 0.70 | GABRA1 (0.37) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL9690728 | 0.68 | RXFP1 (0.46) | TP53POLBMAPTGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483027-A2 | Triazolopyridazines, methods for their preparation, their use as herbicides and intermediates | RHONE-POULENC AGROCHIMIE (FR) | 1992-04-29 | — | — | EP | disclosed |