Sulfuric Acid

Sulfuric Acid

SCHEMBL9689214

C=CCc1c2cccc1OOCC2.O=S(=O)(O)O

nearest known ligand 0.31

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
TSHR P16473 1/20 0.31
PMP22 Q01453 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL7193359 0.99 LMNA (0.30) LMNATHRBTSHRPMP22HSD17B10
Phosphonic Acid SCHEMBL28911452 0.90
SCHEMBL11080714 0.80
SCHEMBL15768107 0.78 CYP1A2 (0.33)
Phosphonic Acid SCHEMBL28552073 0.78
Sulfuric Acid SCHEMBL28160223 0.76 TSHR (0.38) LMNATHRBTSHRPMP22HSD17B10
Sulfuric Acid SCHEMBL1424850 0.75 CYP1A1 (0.35)
Sulfuric Acid SCHEMBL6576620 0.74 CYP1A1 (0.34)
Sulfuric Acid SCHEMBL8521348 0.74 CYP1A1 (0.34)
Sulfuric Acid SCHEMBL3524453 0.70 NFE2L2 (0.35) LMNATHRBTSHRPMP22HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4696760-A Method for production of aqueous dispersion of N-substituted N',N'-alkylene urea NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1987-09-29 US claimed
US-5143546-A Inks with adhesion which varies with voltage CANON KABUSHIKI KAISHA (JP) 1992-09-01 US disclosed
US-5017223-A Liquid Dispersion Of An Electrolyte Capable Of Changing Its Adhesiveness In Response To Voltage Application CANON KABUSHIKI KAISHA (JP) 1991-05-21 US disclosed
EP-0352796-A2 Recording material CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
US-4696760-A Method for production of aqueous dispersion of N-substituted N',N'-alkylene urea NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1987-09-29 US disclosed
US-4578314-A ABRASIVE PARTICLES IN DISPERSION TDK CORPORATION (JP) 1986-03-25 US disclosed