SCHEMBL9689656

SCHEMBL9689656

CCC(C)COc1ccc(O)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.38
TLR8 Q9NR97 1/20 0.38
MCHR1 Q99705 1/20 0.38
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
MAPT P10636 1/20 0.34
ACHE P22303 1/20 0.34
GPR88 Q9GZN0 5/20 0.33
IGF1R P08069 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24355978 0.83 FFAR1 (0.33) FFAR1TLR8MCHR1PDE4APDE4B
SCHEMBL24355956 0.83 FFAR1 (0.33) FFAR1TLR8MCHR1PDE4APDE4B
SCHEMBL23269977 0.82 HTR1A (0.38) MAPT
SCHEMBL23269979 0.82 HTR1A (0.38) MAPT
SCHEMBL26770016 0.80 CYP1A2 (0.39) FFAR1TLR8MCHR1PDE4APDE4B
SCHEMBL28038952 0.80 ALDH1A1 (0.46) PDE4APDE4BPDE4CPDE4D
SCHEMBL423475 0.80 ALDH1A1 (0.46) PDE4APDE4BPDE4CPDE4D
SCHEMBL28111866 0.78 KMT2A (0.35) MAPT
Benzene SCHEMBL28823441 0.77 ALDH1A1 (0.43) PDE4APDE4BPDE4CPDE4D
SCHEMBL13586406 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515972-A1 Polymerizable liquid crystal materials and polymer compositions displaying ferroelectric smectic liquid crystal phases MERCK PATENT GmbH (DE) 1992-12-02 EP disclosed