Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367968 | 0.79 | KIF11 (0.51) | KIF11SLC22A12GAAMCL1MAPT | |
| SCHEMBL31021468 | 0.78 | KIF11 (0.47) | KIF11SLC22A12GAATRPV1MCL1 | |
| SCHEMBL31021464 | 0.78 | KIF11 (0.47) | KIF11SLC22A12GAATRPV1MCL1 | |
| SCHEMBL30994964 | 0.78 | KIF11 (0.50) | KIF11SLC22A12GAATRPV1MCL1 | |
| SCHEMBL2973571 | 0.78 | KIF11 (0.50) | KIF11SLC22A12GAATRPV1MCL1 | |
| SCHEMBL953826 | 0.77 | TRPA1 (0.42) | GAAPOLBMAPTCYP2D6CYP2C9 | |
| SCHEMBL955167 | 0.76 | PTPN5 (0.43) | POLBMAPTCYP2D6CYP2C9 | |
| SCHEMBL4556987 | 0.76 | ALOX5AP (0.41) | KIF11GAAPOLBMAPT | |
| SCHEMBL30487705 | 0.76 | ALOX5AP (0.41) | KIF11GAAPOLBMAPT | |
| SCHEMBL30505745 | 0.76 | SLC22A12 (0.55) | SLC22A12NR3C1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506709-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991008207-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |