SCHEMBL30487705

SCHEMBL30487705

CS(=O)(=O)c1cc(C(F)(F)F)ccc1C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
DDR1 Q08345 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ADRA1A P35348 1/20 0.38
PDE2A O00408 1/20 0.38
KIF11 P52732 2/20 0.37
PTGS2 P35354 1/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 1/20 0.36
ABCB11 O95342 1/20 0.36
GAA P10253 1/20 0.35
CNR2 P34972 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556987 1.00 ALOX5AP (0.41) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL6956211 0.83 POLB (0.39) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL28230701 0.80 ALOX5AP (0.46) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL2798301 0.79 GAA (0.39) ALOX5APFEN1DDR1ALDH1A1KMT2A
SCHEMBL13233065 0.79 GAA (0.39) ALOX5APFEN1DDR1ALDH1A1KMT2A
SCHEMBL16495014 0.78 HSD11B1 (0.44) ALDH1A1TSHRMAPTCNR2LMNA
SCHEMBL23841300 0.77 CES2 (0.47) ALOX5APFEN1DDR1MEN1ALDH1A1
SCHEMBL12335461 0.77 ALOX5AP (0.50) ALOX5APFEN1MEN1ALDH1A1TSHR
SCHEMBL6076943 0.77 KDM4E (0.41) ALOX5APFEN1ALDH1A1ADRA1APTGS2
SCHEMBL16021159 0.77 MCL1 (0.47) ALOX5APFEN1MEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4723888-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS Speedagro Inc. (US) 2026-04-15 EP claimed
WO-2024254580-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS SPEEDAGRO INC. (US) 2024-12-12 WO claimed
EP-4723888-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS Speedagro Inc. (US) 2026-04-15 EP disclosed
US-20250099448-A1 HETEROCYCLIC COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-03-27 US disclosed
US-20250043302-A1 MUTATED HYDROXYPHENYLPYRUVATE DIOXYGENASE POLYPEPTIDE, AND CODING GENE AND USE THEREOF BEIJING DABEINONG BIOTECHNOLOGY CO., LTD. (CN) 2025-02-06 US disclosed
WO-2024254580-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS SPEEDAGRO INC. (US) 2024-12-12 WO disclosed
US-20230212587-A1 Mutant Hydroxyphenylpyruvate Dioxygenase Polypeptide, Encoding Gene Thereof and Use Therefor BEIJING DABEINONG BIOTECHNOLOGY CO. LTD. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099448-A1 HETEROCYCLIC COMPOUNDS OPRM1, CYP1A1, CYP3A4 ALOX5AP 2464/4885FEN1 4564/4885DDR1 4311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.